Dr. Jannis Meents

Since 08/2014
PostDoc in the group of Prof Angelika Lampert at the Institute for Physiology, Universitätsklinikum RWTH Aachen

2010 - 2014
PhD in the group of Prof Peter McNaughton at the Department of Pharmacology, University of Cambridge, UK
Thesis on the modulation of the irritant-sensing ion channel TRPA1 during inflammation and by repetitive activation

2009 – 2010
Research Associate in the group of Dr Uwe Reuter at the Institute for Experimental Neurology, Charité Universitätsmedizin Berlin
Project: Assessed a new TRPV1 antagonist for its efficacy in the treatment of migraine using in vivo models

2006 – 2009
Diploma in Biological Sciences with focus on animal physiology, Humboldt-Universität Berlin
Thesis on the inflammatory regulation of the TRPV1 ion channel expression in trigeminal ganglion neurons during migraine

2003 – 2006
Undergraduate Study of Biological Sciences, Pre-diploma, Johannes Gutenberg-Universität Mainz

Research Interests:

• Voltage-gated sodium channels
• TRP channels
• Molecular basis of pain sensation 

Publications

Meents J.E., Fischer M.J.M., McNaughton P.A. (submitted)
TRPA1 sensitization by Protein Kinase A

Meents J.E., Fischer M.J.M., McNaughton P.A. (2016)
Agonist-induced sensitization of the irritant receptor ion channel TRPA1.
J Physiol.

Meents J.E., Lampert A. (2016)
Studying Sodium Channel Gating in Heterologous Expression Systems.
In: Advanced Patch-Clamp Analysis for Neuroscientists, ed. Korngreen A., Neuromethods, vol. 113. Springer New York.

Meents J.E., Hoffmann J., Reuter U. (2015)
Two new TRPV1 receptor antagonists are effective in two different experimental models of migraine.
J Headache Pain; 16:57

Meents J.E., Neeb L., Reuter U. (2010)
TRPV1 in migraine pathophysiology.
Trends Mol Med; 16(4):153-9

Neeb L., Meents J., Reuter U. (2010)
5-HT1F receptor agonists - A new treatment option for migraine attacks?Neurotherapeutics; 7(2):176-82