(NUP88) lead to the lethal disorder fetal akinesia deformation sequence (FADS). FADS is known to be caused by defect signalling at the neuromuscular junction, the synapse where a motor neuron transmits a [...] for a medical thesis. Fetal akinesia deformation sequence (FADS) is a lethal neuromuscular disorder caused by defective proteins of the neuromuscular junction. Affected fetuses present with an inability to [...] Vermeersch M, Supply L, Martins N, Pirenne L, et al. 2018. Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence. PLoS Genet 14:e1007845. Jühlen R and Fahrenkrog B. 2018
t Göteborg wurden die Ergebnisse in „BRAIN“ publiziert. Originalpublikation: Loss of supervillin causes myopathy with myofibrillar disorganization and autophagic vacuoles Carola Hedberg-Oldfors 1,* , Robert
t Göteborg wurden die Ergebnisse in „BRAIN“ publiziert. Originalpublikation: Loss of supervillin causes myopathy with myofibrillar disorganization and autophagic vacuoles Carola Hedberg-Oldfors 1,* , Robert
of great importance for understanding the pathogenesis of diseases, especially when the disease is caused by a previously unknown pathogen such as SARS-CoV (2002, worldwide), MERS-CoV (2012, Arabia), SARS-CoV-2
the prototypic example of the step-wise development of BM fibrosis. The specific mechanisms that cause BM fibrosis are not understood, in particular as the cells driving fibrosis remained obscure for a [...] state-of-the-art techniques to unravel the complex molecular and cellular interaction between fibrosis-causing cells and the malignant hematopoietic cells to ultimately develop novel targeted therapies with curative
1080/10447318.2023.2260973 Lipprandt M, Liedke W, Langanke M, Klausen A, Baumgarten N, Röhrig R : Causes of adverse events in home mechanical ventilation: a nursing perspective. BMC Nursing volume 21, Article [...] Article number: 264 (2022) doi: 10.1186/s12912-022-01038-2 Coldewey B , Diruf A, Röhrig R, Lipprandt M. Causes of use errors in ventilation devices - Systematic review. Applied Ergonomics 2022; 98:103544. doi:
schizophrenia “Functional and structural changes in the brain have until now mainly been regarded as the cause or consequence of mental illness. However, there is evidence suggesting that drug and psychotherapeutic
body, may play a minor role in analgesia but may explain the known side effect of taste disturbances caused by diclofenac. Details on the identification of ATA and Diclofenac as a P2X3R antagonists can be
Wasik M, Koschmieder S, Green TR, Skoda RC, Skorski T. Ruxolitinib-induced defects in DNA repair cause sensitivity to PARP inhibitors in myeloproliferative neoplasms; Blood. 2017 Dec 28;130(26):2848-2859
g provides an alternative strategy to tackle the problems of autograft and allograft procedures, caused by lack of donor tissues, supply limitations and rejections by the recipients’ immune system. In