Veröffentlichungen von Prof. Joachim Jankowski in den letzten 5 Jahren:

 

Jankowski, Joachim - Search Results - PubMed (nih.gov)

  1. Noels H, Jankowski V, Schunk SJ, Vanholder R, Kalim S and Jankowski J. Post-translational modifications in kidney diseases and associated cardiovascular risk. Nat Rev Nephrol. 2024.
     
  2. Moellmann J, Krueger K, Wong DWL, Klinkhammer BM, Buhl EM, Dehairs J, Swinnen JV, Noels H, Jankowski J, Lebherz C, Boor P, Marx N and Lehrke M. 2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function. Biochim Biophys Acta Mol Basis Dis. 2024;1870:166825.
     
  3. Mavrogeorgis E, Valkenburg S, Siwy J, Latosinska A, Glorieux G, Mischak H and Jankowski J. Integration of Urinary Peptidome and Fecal Microbiome to Explore Patient Clustering in Chronic Kidney Disease. Proteomes. 2024;12.
     
  4. Jaimes Campos MA, Mavrogeorgis E, Latosinska A, Eder S, Buchwinkler L, Mischak H, Siwy J, Rossing P, Mayer G and Jankowski J. Urinary peptide analysis to predict the response to blood pressure medication. Nephrol Dial Transplant. 2024;39:873-883.
     
  5. Harlacher E, Schulte C, Vondenhoff S, Schmitt-Kopplin P, Diederich P, Hemmers C, Moellmann J, Wollenhaupt J, Veltrop R, Biessen E, Lehrke M, Peters B, Schlieper G, Kuppe C, Floege J, Jankowski V, Marx N, Jankowski J and Noels H. Increased levels of a mycophenolic acid metabolite in patients with kidney failure negatively affect cardiomyocyte health. Front Cardiovasc Med. 2024;11:1346475.
     
  6. Curaj A, Vanholder R, Loscalzo J, Quach K, Wu Z, Jankowski V and Jankowski J. Cardiovascular Consequences of Uremic Metabolites: an Overview of the Involved Signaling Pathways. Circ Res. 2024;134:592-613.
     
  7. Rama E, Mohapatra SR, Sugimura Y, Suzuki T, Siebert S, Barmin R, Hermann J, Baier J, Rix A, Lemainque T, Koletnik S, Elshafei AS, Pallares RM, Dadfar SM, Tolba RH, Schulz V, Jankowski J, Apel C, Akhyari P, Jockenhoevel S and Kiessling F. In vitro and in vivo evaluation of biohybrid tissue-engineered vascular grafts with transformative (1)H/(19)F MRI traceable scaffolds. Biomaterials. 2024;311:122669.
     
  8. Mina IK, Mavrogeorgis E, Siwy J, Stojanov R, Mischak H, Latosinska A and Jankowski V. Multiple urinary peptides display distinct sex-specific distribution. Proteomics. 2024;24:e2300227.
     
  9. Knaup I, Kramann R, Sasula MJ, Mack P, Bastos Craveiro R, Niederau C, Coenen F, Neuss S, Jankowski J and Wolf M. TNF reduces osteogenic cell fate in PDL cells at transcriptional and functional levels without alteration of periodontal proliferative capacity. J Orofac Orthop. 2024.
     
  10. Darguzyte M, Rama E, Rix A, Baier J, Hermann J, Rezvantalab S, Khedri M, Jankowski J and Kiessling F. Riboflavin-targeted polymers improve tolerance of paclitaxel while maintaining therapeutic efficacy. Nanomedicine. 2024;58:102751.
     
  11. Buse M, Cheng M, Jankowski V, Lellig M, Sterzer V, Strieder T, Leuchtle K, Martin IV, Seikrit C, Brinkkoettter P, Crispatzu G, Floege J, Boor P, Speer T, Kramann R, Ostendorf T, Moeller MJ, Costa IG and Stamellou E. Lineage tracing reveals transient phenotypic adaptation of tubular cells during acute kidney injury. iScience. 2024;27:109255.
  12. Mouzakis FL, Hima F, Kashefi A, Greven J, Rink L, van der Vorst EPC, Jankowski J, Mottaghy K and Spillner J. Molecular Hydrogen and Extracorporeal Gas Exchange: A Match Made in Heaven? An In Vitro Pilot Study. Biomedicines. 2024;12.
     
  13. Lellig M, Rodriguez M, Lopez-Baltanas R, Hermann J, Wollenhaupt J, Noels H, Zidek W, Tepel M, Mahfoud F, Jankowski J, Munoz-Castaneda JR and Jankowski V. Pyridoxal-5'-phosphate: A cost-effective treatment candidate for hypertensive patients? J Intern Med. 2024;296:435-448.
     
  14. Katahira S, Barth M, Dopp R, Sugimura Y, Schmidt V, Selig JI, Saiki Y, Jankowski J, Marx N, Jahnen-Dechent W, Lichtenberg A and Akhyari P. Pioglitazone treatment mitigates cardiovascular bioprosthetic degeneration in a chronic kidney disease model. Front Pharmacol. 2024;15:1412169.
     
  15. Hoeft K, Koch L, Ziegler S, Zhang L, Luetke S, Tanzer MC, Mohanta D, Schumacher D, Schreibing F, Long Q, Kim H, Klinkhammer BM, Schikarski C, Maryam S, Baens M, Hermann J, Krieg S, Peisker F, De Laporte L, Schaefer GJ, Menzel S, Jankowski J, Humphreys BD, Wahida A, Schneider RK, Versele M, Boor P, Mann M, Sengle G, Hayat S and Kramann R. ADAMTS12 promotes fibrosis by restructuring extracellular matrix to enable activation of injury-responsive fibroblasts. J Clin Invest. 2024;134.
     
  16. Adam S, Maas SL, Huchzermeier R, Rakateli L, Abschlag K, Hohl M, Liao L, Bartneck M, Teunissen M, Wouters K, Santovito D, Jankowski J, Biessen EAL and van der Vorst EPC. The calcium-sensing-receptor (CaSR) in adipocytes contributes to sex-differences in the susceptibility to high fat diet induced obesity and atherosclerosis. EBioMedicine. 2024;107:105293.
  1. Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, Klug M, Schunk SJ, Schmit D, Kramann R, Korbel C, Ampofo E, Laschke MW, Selejan SR, Paschen A, Herter T, Gaul S, Silbernagel G, Sester M, Sester U, Assmann G, Bals R, Kostner G, Jahnen-Dechent W, Menger MD, Rohrer L, Marz W, Bohm M, Jankowski J, Kopf M, Latz E, Niemeyer BA, Fliser D, Laufs U and Speer T. Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form. Nat Immunol. 2023;24:412-413.
     
  2. Wu Z, Lohmoller J, Kuhl C, Wehrle K and Jankowski J. Use of Computation Ecosystems to Analyze the Kidney-Heart Crosstalk. Circ Res. 2023;132:1084-1100.
     
  3. Soppert J, Brandt EF, Heussen NM, Barzakova E, Blank LM, Kuepfer L, Hornef MW, Trebicka J, Jankowski J, Berres ML and Noels H. Blood Endotoxin Levels as Biomarker of Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2023;21:2746-2758.
     
  4. Roth CE, Niederau C, Radermacher C, Rizk M, Neuss S, Jankowski J, Apel C, Craveiro RB and Wolf M. Knockout of bone sialoprotein in cementoblasts cell lines affects specific gene expression in unstimulated and mechanically stimulated conditions. Ann Anat. 2023;249:152102.
     
  5. Rajput A, Sharma P, Singh D, Singh S, Kaur P, Attri S, Mohana P, Kaur H, Rashid F, Bhatia A, Jankowski J, Arora V, Tuli HS and Arora S. Role of polyphenolic compounds and their nanoformulations: a comprehensive review on cross-talk between chronic kidney and cardiovascular diseases. Naunyn Schmiedebergs Arch Pharmacol. 2023;396:901-924.
     
  6. Noels H and Jankowski J. Increased Risk of Cardiovascular Complications in Chronic Kidney Disease: Introduction to a Compendium. Circ Res. 2023;132:899-901.
     
  7. Moellmann J, Krueger K, Wong DWL, Klinkhammer BM, Buhl EM, Dehairs J, Swinnen JV, Noels H, Jankowski J, Lebherz C, Boor P, Marx N and Lehrke M. 2,8-Dihydroxyadenine-induced nephropathy causes hexosylceramide accumulation with increased mTOR signaling, reduced levels of protective SirT3 expression and impaired renal mitochondrial function. Biochim Biophys Acta Mol Basis Dis. 2023;1870:166825.
     
  8. Marx N, Wanner C, Jankowski J, Marz W, Krane V and Genser B. Recurrent cardiovascular events in patients with type 2 diabetes and haemodialysis: analysis from the 4D Study. Clin Kidney J. 2023;16:1612-1621.
     
  9. Lohia S, Latosinska A, Zoidakis J, Makridakis M, Mischak H, Glorieux G, Vlahou A and Jankowski V. Glycosylation Analysis of Urinary Peptidome Highlights IGF2 Glycopeptides in Association with CKD. Int J Mol Sci. 2023;24.
     
  10. Jaimes Campos MA, Andujar I, Keller F, Mayer G, Rossing P, Staessen JA, Delles C, Beige J, Glorieux G, Clark AL, Mullen W, Schanstra JP, Vlahou A, Rossing K, Peter K, Ortiz A, Campbell A, Persson F, Latosinska A, Mischak H, Siwy J and Jankowski J. Prognosis and Personalized In Silico Prediction of Treatment Efficacy in Cardiovascular and Chronic Kidney Disease: A Proof-of-Concept Study. Pharmaceuticals (Basel). 2023;16.
     
  11. Geisler F, Remmelzwaal S, Jankowski V, Schmidt R, Boxem M and Leube RE. Intermediate filament network perturbation in the C. elegans intestine causes systemic dysfunctions. Elife. 2023;12.
     
  12. Bhargava S, Jankowski J, Merckelbach E, Roth CE, Craveiro RB and Wolf M. Development, Establishment, and Validation of a Model for the Mineralization of Periodontium Remodelling Cells: Cementoblasts. Int J Mol Sci. 2023;24.
     
  13. Bhargava S and Jankowski J. The PRIDE database resources in 2023. Nephrol Dial Transplant. 2023.
     
  14. Bhargava S and Jankowski J. Fosl1: friend or foe? Kidney Int. 2023;103:656-658.
  1. Wu Z, Jankowski V and Jankowski J. Irreversible post-translational modifications - Emerging cardiovascular risk factors. Mol Aspects Med. 2022;86:101010.
     
  2. Wu Z and Jankowski J. Impact of post-translational modification on the genesis and progression of diseases. Mol Aspects Med. 2022;86:101105.
     
  3. Wollenhaupt J, Frisch J, Harlacher E, Wong DWL, Jin H, Schulte C, Vondenhoff S, Moellmann J, Klinkhammer BM, Zhang L, Baleanu-Curaj A, Liehn EA, Speer T, Kazakov A, Werner C, van der Vorst EPC, Selejan SR, Hohl M, Bohm M, Kramann R, Biessen EAL, Lehrke M, Marx N, Jankowski J, Maack C, Boor P, Prates Roma L and Noels H. Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease. Redox Biol. 2022;56:102459.
     
  4. Thiele K, Rau M, Hartmann NK, Moller M, Mollmann J, Jankowski J, Keszei AP, Bohm M, Floege J, Marx N and Lehrke M. Empagliflozin reduces markers of acute kidney injury in patients with acute decompensated heart failure. ESC Heart Fail. 2022;9:2233-2238.
     
  5. Soppert J, Frisch J, Wirth J, Hemmers C, Boor P, Kramann R, Vondenhoff S, Moellmann J, Lehrke M, Hohl M, van der Vorst EPC, Werner C, Speer T, Maack C, Marx N, Jankowski J, Roma LP and Noels H. A systematic review and meta-analysis of murine models of uremic cardiomyopathy. Kidney Int. 2022;101:256-273.
     
  6. Soppert J, Brandt EF, Heussen NM, Barzakova E, Blank LM, Kuepfer L, Hornef MW, Trebicka J, Jankowski J, Berres ML and Noels H. Blood Endotoxin Levels as Biomarker of Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2022.
     
  7. Roth CE, Craveiro RB, Niederau C, Malyaran H, Neuss S, Jankowski J and Wolf M. Mechanical Compression by Simulating Orthodontic Tooth Movement in an In Vitro Model Modulates Phosphorylation of AKT and MAPKs via TLR4 in Human Periodontal Ligament Cells. Int J Mol Sci. 2022;23.
     
  8. Petra E, Siwy J, Vlahou A and Jankowski J. Urine peptidome in combination with transcriptomics analysis highlights MMP7, MMP14 and PCSK5 for further investigation in chronic kidney disease. PLoS One. 2022;17:e0262667.
     
  9. Peters LJF, Baaten C, Maas SL, Lu C, Nagy M, Jooss NJ, Bidzhekov K, Santovito D, Moreno-Andres D, Jankowski J, Biessen EAL, Doring Y, Heemskerk JWM, Weber C, Kuijpers MJE and van der Vorst EPC. MicroRNA-26b Attenuates Platelet Adhesion and Aggregation in Mice. Biomedicines. 2022;10.
     
  10. Niederau C, Bhargava S, Schneider-Kramman R, Jankowski J, Craveiro RB and Wolf M. Xanthohumol exerts anti-inflammatory effects in an in vitro model of mechanically stimulated cementoblasts. Sci Rep. 2022;12:14970.
     
  11. Knaup I, Bastian A, Mack P, Sasula MJ, Niederau C, Roth C, Jankowski J and Wolf M. Potential donor-dependent regulative effects of endogenous sclerostin expression and mineralization potential in primary human PDL cells in vitro. Ann Anat. 2022;244:151980.
     
  12. Jiang T, Samapati R, Klassen S, Lei D, Erfinanda L, Jankowski V, Simmons S, Yin J, Arenz C, Dietrich A, Gudermann T, Adam D, Schaefer M, Jankowski J, Flockerzi V, Nusing R, Uhlig S and Kuebler WM. Stimulation of the EP(3) receptor causes lung oedema by activation of TRPC6 in pulmonary endothelial cells. Eur Respir J. 2022;60.
     
  13. Jiang T, Samapati R, Klassen S, Lei D, Erfinanda L, Jankowski V, Simmons S, Yin J, Arenz C, Dietrich A, Gudermann T, Adam D, Schaefer M, Jankowski J, Flockerzi V, Nusing R, Uhlig S and Kuebler WM. Stimulation of the EP3 receptor causes lung edema by activation of TRPC6 in pulmonary endothelial cells. Eur Respir J. 2022.
     
  14. Jankowski V, Saritas T, Kjolby M, Hermann J, Speer T, Himmelsbach A, Mahr K, Heuschkel MA, Schunk SJ, Thirup S, Winther S, Bottcher M, Nyegard M, Nykjaer A, Kramann R, Kaesler N, Jankowski J, Floege J, Marx N and Goettsch C. Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease. Kidney Int. 2022;101:574-584.
     
  15. Hemmers C, Schulte C, Wollenhaupt J, Wong DWL, Harlacher E, Orth-Alampour S, Klinkhammer BM, Schirmer SH, Bohm M, Marx N, Speer T, Boor P, Jankowski J and Noels H. Chemokine CCL9 Is Upregulated Early in Chronic Kidney Disease and Counteracts Kidney Inflammation and Fibrosis. Biomedicines. 2022;10.
     
  16. Bohler H, Orth-Alampour S, Baaten C, Riedner M, Jankowski J and Beck T. Assembly of chemically modified protein nanocages into 3D materials for the adsorption of uremic toxins. J Mater Chem B. 2022;11:55-60.
     
  17. Bhargava S, Merckelbach E, Noels H, Vohra A and Jankowski J. Homeostasis in the Gut Microbiota in Chronic Kidney Disease. Toxins (Basel). 2022;14.
     
  18. Bhargava S, de la Puente-Secades S, Schurgers L and Jankowski J. Lipids and lipoproteins in cardiovascular diseases: a classification. Trends Endocrinol Metab. 2022;33:409-423.
     
  19. Baaten C, Schroer JR, Floege J, Marx N, Jankowski J, Berger M and Noels H. Platelet Abnormalities in CKD and Their Implications for Antiplatelet Therapy. Clin J Am Soc Nephrol. 2022;17:155-170.


Stand: Feb 2023

  1. Wu Z, Jankowski V and Jankowski J. Irreversible post-translational modifications - Emerging cardiovascular risk factors. Mol Aspects Med. 2021:101010.
     
  2. Vlahou A, Hallinan D, Apweiler R, Argiles A, Beige J, Benigni A, Bischoff R, Black PC, Boehm F, Ceraline J, Chrousos GP, Delles C, Evenepoel P, Fridolin I, Glorieux G, van Gool AJ, Heidegger I, Ioannidis JPA, Jankowski J, Jankowski V, Jeronimo C, Kamat AM, Masereeuw R, Mayer G, Mischak H, Ortiz A, Remuzzi G, Rossing P, Schanstra JP, Schmitz-Drager BJ, Spasovski G, Staessen JA, Stamatialis D, Stenvinkel P, Wanner C, Williams SB, Zannad F, Zoccali C and Vanholder R. Data Sharing Under the General Data Protection Regulation: Time to Harmonize Law and Research Ethics? Hypertension. 2021;77:1029-1035.
     
  3. Vanholder R, Argiles A, Jankowski J and European Uraemic Toxin Work G. A history of uraemic toxicity and of the European Uraemic Toxin Work Group (EUTox). Clin Kidney J. 2021;14:1514-1523.
     
  4. Thiele K, Rau M, Hartmann NK, Mollmann J, Jankowski J, Bohm M, Keszei AP, Marx N and Lehrke M. Effects of empagliflozin on erythropoiesis in patients with type 2 diabetes: Data from a randomized, placebo-controlled study. Diabetes Obes Metab. 2021;23:2814-2818.
     
  5. Sundararaman SS, Peters LJF, Jansen Y, Gencer S, Yan Y, Nazir S, Bonnin Marquez A, Kahles F, Lehrke M, Biessen EAL, Jankowski J, Weber C, Doring Y and van der Vorst EPC. Adipocyte calcium sensing receptor is not involved in visceral adipose tissue inflammation or atherosclerosis development in hyperlipidemic Apoe(-/-) mice. Sci Rep. 2021;11:10409.
     
  6. Soppert J, Frisch J, Wirth J, Hemmers C, Boor P, Kramann R, Vondenhoff S, Moellmann J, Lehrke M, Hohl M, van der Vorst EPC, Werner C, Speer T, Maack C, Marx N, Jankowski J, Roma LP and Noels H. A systematic review and meta-analysis of murine models of uremic cardiomyopathy. Kidney Int. 2021.
     
  7. Schunk SJ, Hermann J, Sarakpi T, Triem S, Lellig M, Hahm E, Zewinger S, Schmit D, Becker E, Mollmann J, Lehrke M, Kramann R, Boor P, Lipp P, Laufs U, Marz W, Reiser J, Jankowski J, Fliser D, Speer T and Jankowski V. Guanidinylated Apolipoprotein C3 (ApoC3) Associates with Kidney and Vascular Injury. J Am Soc Nephrol. 2021.
     
  8. Schumacher D, Liehn EA, Singh A, Curaj A, Wijnands E, Lira SA, Tacke F, Jankowski J, Biessen EAL and van der Vorst EPC. CCR6 Deficiency Increases Infarct Size after Murine Acute Myocardial Infarction.Biomedicines. 2021;9.
     
  9. Saar-Kovrov V, Zidek W, Orth-Alampour S, Fliser D, Jankowski V, Biessen EAL and Jankowski J. Reduction of protein-bound uraemic toxins in plasma of chronic renal failure patients: A systematic review. J Intern Med. 2021;290:499-526.
     
  10. Petra E, He T, Lygirou V, Latosinska A, Mischak H, Vlahou A and Jankowski J. Urine peptidome analysis in cardiorenal syndrome reflects molecular processes. Sci Rep. 2021;11:16219.
     
  11. Orth-Alampour S, Gayrard N, Salem S, Bhargava S, Jankowski V, Jover B, Notarnicola C, Noels H, van der Vorst EPC, Kuppe C, Wolf M, Goettsch C, Theelen W, Bruck H, Fliser D, Loscalzo J, Wu Z, Marx N, Zidek W, Argiles A and Jankowski J. Prevention of vascular calcification by the endogenous chromogranin A-derived mediator that inhibits osteogenic transdifferentiation. Basic Res Cardiol. 2021;116:57.
     
  12. Noels H, Lehrke M, Vanholder R and Jankowski J. Lipoproteins and fatty acids in chronic kidney disease: molecular and metabolic alterations. Nat Rev Nephrol. 2021;17:528-542.
     
  13. Mavrogeorgis E, Mischak H, Latosinska A, Siwy J, Jankowski V and Jankowski J. Reproducibility Evaluation of Urinary Peptide Detection Using CE-MS. Molecules. 2021;26.
     
  14. Jankowski V, Saritas T, Kjolby M, Hermann J, Speer T, Himmelsbach A, Mahr K, Heuschkel MA, Schunk SJ, Thirup S, Winther S, Bottcher M, Nyegard M, Nykjaer A, Kramann R, Kaesler N, Jankowski J, Floege J, Marx N and Goettsch C. Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease. Kidney Int. 2021.
     
  15. Jankowski J, Floege J, Fliser D, Bohm M and Marx N. Cardiovascular Disease in Chronic Kidney Disease: Pathophysiological Insights and Therapeutic Options. Circulation. 2021;143:1157-1172.
     
  16. Hermann J, Brehmer K, Jankowski V, Lellig M, Hohl M, Mahfoud F, Speer T, Schunk SJ, Tschernig T, Thiele H and Jankowski J. Registration of Image Modalities for Analyses of Tissue Samples Using 3D Image Modelling. Proteomics Clin Appl. 2021;15:e2170024.
     
  17. Brockhaus J, Craveiro RB, Azraq I, Niederau C, Schroder SK, Weiskirchen R, Jankowski J and Wolf M. In Vitro Compression Model for Orthodontic Tooth Movement Modulates Human Periodontal Ligament Fibroblast Proliferation, Apoptosis and Cell Cycle. Biomolecules. 2021;11.
     
  18. Baaten C, Sternkopf M, Henning T, Marx N, Jankowski J and Noels H. Platelet Function in CKD: A Systematic Review and Meta-Analysis.J Am Soc Nephrol. 2021.
     
  19. Baaten C, Schroer J, Floege J, Marx N, Jankowski J, Berger M and Noels H. Platelet Abnormalities in Chronic Kidney Disease and Their Implications for Antiplatelet Therapy. Clin J Am Soc Nephrol. 2021.
  1. Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, Klug M, Schunk SJ, Schmit D, Kramann R, Korbel C, Ampofo E, Laschke MW, Selejan SR, Paschen A, Herter T, Schuster S, Silbernagel G, Sester M, Sester U, Assmann G, Bals R, Kostner G, Jahnen-Dechent W, Menger MD, Rohrer L, Marz W, Bohm M, Jankowski J, Kopf M, Latz E, Niemeyer BA, Fliser D, Laufs U and Speer T. Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation. Nat Immunol. 2020;21:30-41.
     
  2. Wu Z, Bagarolo GI, Thoroe-Boveleth S and Jankowski J. "Lipidomics": Mass spectrometric and chemometric analyses of lipids. Adv Drug Deliv Rev. 2020;159:294-307.
     
  3. Tsukada J, Wolf F, Vogt F, Schaaps N, Thoroe-Boveleth S, Keijdener H, Jankowski J, Tsukada H, Jockenhovel S, Jinzaki M, Schmitz-Rode T and Mela P. Development of in vitro endothelialized drug-eluting stent using human peripheral blood-derived endothelial progenitor cells. J Tissue Eng Regen Med. 2020;14:1415-1427.
     
  4. Tilstam PV, Soppert J, Hemmers C, Harlacher E, Doring Y, van der Vorst EPC, Schulte C, Alampour-Rajabi S, Theelen W, Asare Y, de Winther MPJ, Lawrence T, Bernhagen J, Schober A, Zernecke A, Jankowski J, Weber C and Noels H. Non-activatable mutant of inhibitor of kappa B kinase alpha (IKKalpha) exerts vascular site-specific effects on atherosclerosis in Apoe-deficient mice. Atherosclerosis. 2020;292:23-30.
     
  5. Sternkopf M, Nagy M, Baaten C, Kuijpers MJE, Tullemans BME, Wirth J, Theelen W, Mastenbroek TG, Lehrke M, Winnerling B, Baerts L, Marx N, De Meester I, Doring Y, Cosemans J, Daiber A, Steven S, Jankowski J, Heemskerk JWM and Noels H. Native, Intact Glucagon-Like Peptide 1 Is a Natural Suppressor of Thrombus Growth Under Physiological Flow Conditions. Arterioscler Thromb Vasc Biol. 2020;40:e65-e77.
     
  6. Soppert J, Lehrke M, Marx N, Jankowski J and Noels H. Lipoproteins and lipids in cardiovascular disease: from mechanistic insights to therapeutic targeting. Adv Drug Deliv Rev. 2020;159:4-33.
     
  7. Popowski E, Kohl B, Schneider T, Jankowski J and Schulze-Tanzil G. Uremic Toxins and Ciprofloxacin Affect Human Tenocytes In Vitro.Int J Mol Sci. 2020;21.
     
  8. Peters LJF, Floege J, Biessen EAL, Jankowski J and van der Vorst EPC. MicroRNAs in Chronic Kidney Disease: Four Candidates for Clinical Application. Int J Mol Sci. 2020;21.
     
  9. Noels H and Jankowski J. Editorial on the Special Issue "Comorbidities in Chronic Kidney Disease". Toxins (Basel). 2020;12.
     
  10. Jankowski J. Proteomic Biomarkers to Guide Stratification for Covid-19 Treatment: Exemplifying a Path Forward Toward Implementation? Proteomics. 2020;20:e2000229.
     
  11. Holmar J, Noels H, Bohm M, Bhargava S, Jankowski J and Orth-Alampour S. Development, establishment and validation of in vitro and ex vivo assays of vascular calcification. Biochem Biophys Res Commun. 2020;530:462-470.
     
  12. Holmar J, de la Puente-Secades S, Floege J, Noels H, Jankowski J and Orth-Alampour S. Uremic Toxins Affecting Cardiovascular Calcification: A Systematic Review. Cells. 2020;9.
     
  13. Hermann J, Noels H, Theelen W, Lellig M, Orth-Alampour S, Boor P, Jankowski V and Jankowski J. Sample preparation of formalin-fixed paraffin-embedded tissue sections for MALDI-mass spectrometry imaging. Anal Bioanal Chem. 2020;412:1263-1275.
     
  14. Ficheux A, Gayrard N, Szwarc I, Duranton F, Vetromile F, Brunet P, Servel MF, Jankowski J and Argiles A. Measuring intradialyser transmembrane and hydrostatic pressures: pitfalls and relevance in haemodialysis and haemodiafiltration. Clin Kidney J. 2020;13:580-586.
     
  15. Curaj A, Schumacher D, Rusu M, Staudt M, Li X, Simsekyilmaz S, Jankowski V, Jankowski J, Dumitrascu AR, Hausenloy DJ, Schuh A and Liehn EA. Neutrophils Modulate Fibroblast Function and Promote Healing and Scar Formation after Murine Myocardial Infarction. Int J Mol Sci. 2020;21.
     
  16. Asare Y, Koehncke J, Selle J, Simsekyilmaz S, Jankowski J, Shagdarsuren G, Gessner JE, Bernhagen J and Shagdarsuren E. Differential Role for Activating FcgammaRIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis in Apolipoprotein E-Deficient Mice. Front Physiol. 2020;11:673.
  1. Vollmer, T., Ljungberg, B., Jankowski, V., Jankowski, J., Glorieux, G. & Stegmayr, B. G. An in-vitro assay using human spermatozoa to detect toxicity of biologically active substances. Sci Rep 9, 14525, doi:10.1038/s41598-019-50929-z (2019).
     
  2. van der Made, T. K., Fedecostante, M., Scotcher, D., Rostami-Hodjegan, A., Sastre Torano, J., Middel, I., Koster, A. S., Gerritsen, K. G., Jankowski, V., Jankowski, J., Hoenderop, J. G. J., Masereeuw, R. & Galetin, A. Quantitative Translation of Microfluidic Transporter in Vitro Data to in Vivo Reveals Impaired Albumin-Facilitated Indoxyl Sulfate Secretion in Chronic Kidney Disease. Mol Pharm 16, 4551-4562, doi:10.1021/acs.molpharmaceut.9b00681 (2019).
     
  3. Sternkopf, M., Thoroe-Boveleth, S., Beck, T., Oleschko, K., Erlenkotter, A., Tschulena, U., Steppan, S., Speer, T., Goettsch, C., Jankowski, V., Jankowski, J., Noels, H. & European Uremic Toxin Work Group, E. A Bifunctional Adsorber Particle for the Removal of Hydrophobic Uremic Toxins from Whole Blood of Renal Failure Patients. Toxins (Basel) 11, doi:10.3390/toxins11070389 (2019).
     
  4. Schumacher, D., Alampour-Rajabi, S., Ponomariov, V., Curaj, A., Wu, Z., Staudt, M., Rusu, M., Jankowski, V., Marx, N., Jankowski, J., Brandenburg, V., Liehn, E. A. & Schuh, A. Cardiac FGF23: new insights into the role and function of FGF23 after acute myocardial infarction. Cardiovasc Pathol 40, 47-54, doi:10.1016/j.carpath.2019.02.001 (2019).
     
  5. Mossanen, J. C., Kohlhepp, M., Wehr, A., Krenkel, O., Liepelt, A., Roeth, A. A., Mockel, D., Heymann, F., Lammers, T., Gassler, N., Hermann, J., Jankowski, J., Neumann, U. P., Luedde, T., Trautwein, C. & Tacke, F. CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4(+) T-Cell-Dependent Control of Senescence. Gastroenterology 156, 1877-1889 e1874, doi:10.1053/j.gastro.2019.01.247 (2019).
     
  6. Gajjala, P. R., Bruck, H., Noels, H., Heinze, G., Ceccarelli, F., Kribben, A., Saez-Rodriguez, J., Marx, N., Zidek, W., Jankowski, J. & Jankowski, V. Novel plasma peptide markers involved in the pathology of CKD identified using mass spectrometric approach. J Mol Med (Berl) 97, 1451-1463, doi:10.1007/s00109-019-01823-8 (2019).
  1. Seibert, F. S., Bernhard, F., Stervbo, U., Vairavanathan, S., Bauer, F., Rohn, B., Pagonas, N., Babel, N., Jankowski, J. & Westhoff, T. H. The Effect of Microgravity on Central Aortic Blood Pressure. Am J Hypertens 31, 1183-1189, doi:10.1093/ajh/hpy119 (2018).
     
  2. Schmitz, C., Noels, H., El Bounkari, O., Straussfeld, E., Megens, R. T. A., Sternkopf, M., Alampour-Rajabi, S., Krammer, C., Tilstam, P. V., Gerdes, N., Burger, C., Kapurniotu, A., Bucala, R., Jankowski, J., Weber, C. & Bernhagen, J. Mif-deficiency favors an atheroprotective autoantibody phenotype in atherosclerosis. FASEB J 32, 4428-4443, doi:10.1096/fj.201800058R (2018).
     
  3. Sawant, M., Schwarz, N., Windoffer, R., Magin, T. M., Krieger, J., Mucke, N., Obara, B., Jankowski, V., Jankowski, J., Wally, V., Lettner, T. & Leube, R. E. Threonine 150 Phosphorylation of Keratin 5 Is Linked to Epidermolysis Bullosa Simplex and Regulates Filament Assembly and Cell Viability. J Invest Dermatol 138, 627-636, doi:10.1016/j.jid.2017.10.011 (2018).
     
  4. Noels, H., Theelen, W., Sternkopf, M., Jankowski, V., Moellmann, J., Kraemer, S., Lehrke, M., Marx, N., Martin, L., Marx, G., Jankowski, J., Goetzenich, A. & Stoppe, C. Reduced post-operative DPP4 activity associated with worse patient outcome after cardiac surgery. Sci Rep 8, 11820, doi:10.1038/s41598-018-30235-w (2018).
     
  5. Noels, H., Boor, P., Goettsch, C., Hohl, M., Jahnen-Dechent, W., Jankowski, V., Kindermann, I., Kramann, R., Lehrke, M., Linz, D., Maack, C., Niemeyer, B., Roma, L. P., Schuett, K., Speer, T., Wagenpfeil, S., Werner, C., Zewinger, S., Bohm, M., Marx, N., Floege, J., Fliser, D. & Jankowski, J. The new SFB/TRR219 Research Centre. Eur Heart J 39, 975-977, doi:10.1093/eurheartj/ehy083 (2018).
     
  6. Moellmann, J., Klinkhammer, B. M., Onstein, J., Stohr, R., Jankowski, V., Jankowski, J., Lebherz, C., Tacke, F., Marx, N., Boor, P. & Lehrke, M. Glucagon-Like Peptide 1 and Its Cleavage Products Are Renoprotective in Murine Diabetic Nephropathy. Diabetes 67, 2410-2419, doi:10.2337/db17-1212 (2018).
     
  7. Marx, N., Noels, H., Jankowski, J., Floege, J., Fliser, D. & Bohm, M. Mechanisms of cardiovascular complications in chronic kidney disease: research focus of the Transregional Research Consortium SFB TRR219 of the University Hospital Aachen (RWTH) and the Saarland University. Clin Res Cardiol 107, 120-126, doi:10.1007/s00392-018-1260-0 (2018).
     
  8. Magalhaes, P., Pontillo, C., Pejchinovski, M., Siwy, J., Krochmal, M., Makridakis, M., Carrick, E., Klein, J., Mullen, W., Jankowski, J., Vlahou, A., Mischak, H., Schanstra, J. P., Zurbig, P. & Pape, L. Comparison of Urine and Plasma Peptidome Indicates Selectivity in Renal Peptide Handling. Proteomics Clin Appl 12, e1700163, doi:10.1002/prca.201700163 (2018).
     
  9. Kumar, R. K., Heuchel, M., Kratz, K., Lendlein, A., Jankowski, J. & Tetali, S. D. Effects of extracts prepared from modified porous poly(ether imide) microparticulate absorbers on cytotoxicity, macrophage differentiation and proinflammatory behavior of human monocytic (THP-1) cells. Clin Hemorheol Microcirc 69, 175-185, doi:10.3233/CH-189112 (2018).
     
  10. Kork, F., Jankowski, J., Goswami, A., Weis, J., Brook, G., Yamoah, A., Anink, J., Aronica, E., Fritz, S., Huck, C., Schipke, C., Peters, O., Tepel, M., Noels, H. & Jankowski, V. Golgin A4 in CSF and granulovacuolar degenerations of patients with Alzheimer disease. Neurology 91, e1799-e1808, doi:10.1212/WNL.0000000000006457 (2018).
     
  11. Hegner, B., Schaub, T., Janke, D., Zickler, D., Lange, C., Girndt, M., Jankowski, J., Schindler, R. & Dragun, D. Targeting proinflammatory cytokines ameliorates calcifying phenotype conversion of vascular progenitors under uremic conditions in vitro. Sci Rep 8, 12087, doi:10.1038/s41598-018-30626-z (2018).
  1. Siwy, J., Zurbig, P., Argiles, A., Beige, J., Haubitz, M., Jankowski, J., Julian, B. A., Linde, P. G., Marx, D., Mischak, H., Mullen, W., Novak, J., Ortiz, A., Persson, F., Pontillo, C., Rossing, P., Rupprecht, H., Schanstra, J. P., Vlahou, A. & Vanholder, R. Noninvasive diagnosis of chronic kidney diseases using urinary proteome analysis. Nephrol Dial Transplant 32, 2079-2089, doi:10.1093/ndt/gfw337 (2017).
     
  2. Rowinska, Z., Koeppel, T. A., Sanati, M., Schelzig, H., Jankowski, J., Weber, C., Zernecke, A. & Liehn, E. A. Role of the CX3C chemokine receptor CX3CR1 in the pathogenesis of atherosclerosis after aortic transplantation. PLoS One 12, e0170644, doi:10.1371/journal.pone.0170644 (2017).
     
  3. Pontillo, C., Zhang, Z. Y., Schanstra, J. P., Jacobs, L., Zurbig, P., Thijs, L., Ramirez-Torres, A., Heerspink, H. J. L., Lindhardt, M., Klein, R., Orchard, T., Porta, M., Bilous, R. W., Charturvedi, N., Rossing, P., Vlahou, A., Schepers, E., Glorieux, G., Mullen, W., Delles, C., Verhamme, P., Vanholder, R., Staessen, J. A., Mischak, H. & Jankowski, J. Prediction of Chronic Kidney Disease Stage 3 by CKD273, a Urinary Proteomic Biomarker. Kidney Int Rep 2, 1066-1075, doi:10.1016/j.ekir.2017.06.004 (2017).
     
  4. Pontillo, C., Jacobs, L., Staessen, J. A., Schanstra, J. P., Rossing, P., Heerspink, H. J. L., Siwy, J., Mullen, W., Vlahou, A., Mischak, H., Vanholder, R., Zurbig, P. & Jankowski, J. A urinary proteome-based classifier for the early detection of decline in glomerular filtration. Nephrol Dial Transplant 32, 1510-1516, doi:10.1093/ndt/gfw239 (2017).
     
  5. Krochmal, M., Cisek, K., Filip, S., Markoska, K., Orange, C., Zoidakis, J., Gakiopoulou, C., Spasovski, G., Mischak, H., Delles, C., Vlahou, A. & Jankowski, J. Identification of novel molecular signatures of IgA nephropathy through an integrative -omics analysis. Sci Rep 7, 9091, doi:10.1038/s41598-017-09393-w (2017).
     
  6. Krieter, D. H., Devine, E., Korner, T., Ruth, M., Wanner, C., Raine, M., Jankowski, J. & Lemke, H. D. Haemodiafiltration at increased plasma ionic strength for improved protein-bound toxin removal. Acta Physiol (Oxf) 219, 510-520, doi:10.1111/apha.12730 (2017).
     
  7. Kork, F., Balzer, F., Krannich, A., Bernardi, M. H., Eltzschig, H. K., Jankowski, J. & Spies, C. Back-calculating baseline creatinine overestimates prevalence of acute kidney injury with poor sensitivity. Acta Physiol (Oxf) 219, 613-624, doi:10.1111/apha.12763 (2017).
     
  8. Jansen, J., Jankowski, J., Gajjala, P. R., Wetzels, J. F. M. & Masereeuw, R. Disposition and clinical implications of protein-bound uremic toxins. Clin Sci (Lond) 131, 1631-1647, doi:10.1042/CS20160191 (2017).
     
  9. Gajjala, P. R., Jankowski, V., Heinze, G., Bilo, G., Zanchetti, A., Noels, H., Liehn, E., Perco, P., Schulz, A., Delles, C., Kork, F., Biessen, E., Narkiewicz, K., Kawecka-Jaszcz, K., Floege, J., Soranna, D., Zidek, W. & Jankowski, J. Proteomic-Biostatistic Integrated Approach for Finding the Underlying Molecular Determinants of Hypertension in Human Plasma. Hypertension 70, 412-419, doi:10.1161/HYPERTENSIONAHA.116.08906 (2017).
     
  10. Asare, Y., Ommer, M., Azombo, F. A., Alampour-Rajabi, S., Sternkopf, M., Sanati, M., Gijbels, M. J., Schmitz, C., Sinitski, D., Tilstam, P. V., Lue, H., Gessner, A., Lange, D., Schmid, J. A., Weber, C., Dichgans, M., Jankowski, J., Pardi, R., de Winther, M. P., Noels, H. & Bernhagen, J. Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo. Proc Natl Acad Sci U S A 114, E2766-E2775, doi:10.1073/pnas.1618411114 (2017).