Arbeitsgruppe

Research Assistant

Daniel Kaplan, MSc

MD students

Leonie Ziller

Julia Oberdorfer

Simon Maurice Schmitz

Julian Gonzalez

Laura Distelrath

Gobina Mahendran

Master students

Sophia Garczinski

Former Postdoctoral fellows

Thaysa Leite Tagliaferri, PhD

Kevin Simon, PhD

Completed Theses

PhD Thesis

Kevin Simon, PhD
Duality of the lytic phages Sb-1 and NP-3: How well does co-predation work against Staphylococcus aureus and Pseudomonas aeruginosa under varying environmental conditions?

Thaysa Leite Tagliaferri, PhD 
Exploring the CRISP-Cas9 potential to revert Beta-Lactam resistance in clinically relevant gram-negative bacteria 

Simone Latz, PhD 
Untersuchungen zum therapeutischen Potential von Bakteriophagen der Gattungen PB1, phiKZ und LUZ24 gegen multi-resistente Isolate von Pseudomonas aeruginosa

MD Thesis

Lorenz Weber 
Tackling intrinsic antibiotic resistance in Serratia Marcescens with a combination of Ampicillin/Sulbactam and phage SALSA

Tania Mareike Viertel 
Viruses versus bacteria—novel approaches to phage therapy as a tool against multidrug-resistant pathogens

Anne Sonanini 
Genetic variation of the glucose dehydrogenase gene (gdh) in mitis-streptococci from European and African human populations

Berit Brands 
Complementary retrieval of 16S rRNA gene sequences using broad range primers with inosine at the 3'-terminus - implications for the study of microbial diversity

Simone Holtgräwe 
Zusammenhang zwischen methanogenen Archaea und sulfatreduzierenden Mikroorganismen bei Parodontitis

Master thesis

Daniel Kaplan 
Harnessing T7 Bacteriophage for the Delivery of a conjugative CRISPR-Cas9 Plasmid in order to re-sensitize Escherichia coli in planktonic and biofilm cultures

Julia Hilliges-Pusch 
Quantitative analysis of phage and bacterial human fecal indicators in sewage based on droplet digital PCR and attempts for isolating obligate lytic phages against Phocaeicola dorei

Patricia Blum 
Investigation of putative phage-encoded depolymerases targeting Klebsiella pneumoniae

Leonie Graf 
Influence of oxygen availability on bacteriophages competing for the same Escherichia coli host

Tanja Schwab 
Exploring Re-sensitization of antibiotic resistant Enterobacteriaceae using CRISPR-Cas9

Timo Schmitz 
Characterization of lytic bacteriophages against multidrug resistant gram negative bacteria

Priscilla Munoz 
Susceptibility of multi-drug resistant bacterial species from the ESKAPE-group to wound antiseptics

Lisa Häger 
Comparative analyses between the RNA-phage MS2 and the DNA-phage T4 regarding stability, lysis behavior and competition for the same host

Lukas Wagner 
Methodological approaches for the isolation of flagellotropic phages

Patrick Groos
Comparative analysis of the RNA bacteriophage Qbeta and the DNA bacteriophage T7 with respect to different environmental conditions during propagation

Agnes Seeger
Galleria mellonella as infection model to study the impact of phages against gramnegative bacteria and endotoxin release

Laura Distelrath
Collaborative effect of disinfectants and phages against bacteria isolated from human wound infections

Kevin Simon
Synergy of a Twort-like Myovirus with oxacillin against MRSA

Freya Santana Cubas
Wechselwirkungen zwischen Phagen und Antibiotika zur Reduktion von Klebsiella pneumoniae

Mathias Jansen
Confronting multidrug resistant Acinetobacter baumannii with its natural enemy: genomic insights into newly isolated bacteriophages and in vitro analyses of their lytic activity

Amaia Maennling
Untersuchungen zum lytischen Potential verschiedener Bakteriophagen gegen Antibiotika-resistente Isolate von Klebsiella pneumoniae

Assuda Arif
Vergleichende phänotypische und genetische Analysen neu isolierter Bakteriophagen mit lytischem Potential gegen multiresistente Stämme des Enterobacter cloacae-Komplexes

Nathalie Liedke
Isolierung und Charakterisierung lytischer Bakteriophagen gerichtet gegen klinische Stämme von Pseudomonas aeruginosa

Wolfgang Pier
Analyse eines Staphylokokken-Phagen-Cocktails des Eliava-Instituts für Phagenforschung aus Georgien

Simone Latz
Analyse der globalen genetischen Vielfalt des Glukosyltransferase-Gens von Streptococcus sanguinis und sein Potential als Marker für humane Migrationsstudien

Meike Kiesow
Barcode-Amplicon Sequenzierung des Glucosyltransferase-Gens (gtf) von Streptococcus sanguinis als Marker für anthropologische Studien.

Olga Kessler
Biologie Diplomarbeit: Comparative analysis of the streptococcus glycosyltransferase (gtf) and glucose dehydrogenase (gdh) genes as marker for human-microbe coevolution

Bachelor-Thesis

Jenny Pohl 
Enrichment and characterization of environmental bacteriophages with lytic activity against the nosocomial pathogen Klebsiella pneumoniae in combination with ciprofloxacin

Lara Kötter 
Bestimmung der minimalen Phagenkonzentration für die erfolgreiche Isolation aus Umweltproben 

Anna Keller 
Antibacterial strategies against nosocomial bacterial pathogens using a mixture or single phages

Stamatis Spyridonidis 
Exploring the synergistic effect of a bacteriophage and meropenem against multi-drug resistant Pseudomonas aeruginosa

Johanna Metz
Exploring the synergistic effect of meropenem and a Twort-like Myovirus against MRSA and reduction of resistance-development in MSSA with phage-susceptible and resistant Staphylococcus aureus

Anna Verena Stell
Antimikrobielle Effekte eines Staphylococcus aureus spezifischen Bakteriophagen in Kombination mit Oxacillin in der Therapi