Veröffentlichungen von Prof. Vera Jankowski in den letzten 5 Jahren:

  1. Noels H, Jankowski V, Schunk SJ, Vanholder R, Kalim S and Jankowski J. Post-translational modifications in kidney diseases and associated cardiovascular risk. Nat Rev Nephrol. 2024.
     
  2.  Harlacher E, Schulte C, Vondenhoff S, Schmitt-Kopplin P, Diederich P, Hemmers C, Moellmann J, Wollenhaupt J, Veltrop R, Biessen E, Lehrke M, Peters B, Schlieper G, Kuppe C, Floege J, Jankowski V, Marx N, Jankowski J and Noels H. Increased levels of a mycophenolic acid metabolite in patients with kidney failure negatively affect cardiomyocyte health. Front Cardiovasc Med. 2024;11:1346475.
     
  3. Buse M, Cheng M, Jankowski V, Lellig M, Sterzer V, Strieder T, Leuchtle K, Martin IV, Seikrit C, Brinkkoettter P, Crispatzu G, Floege J, Boor P, Speer T, Kramann R, Ostendorf T, Moeller MJ, Costa IG and Stamellou E. Lineage tracing reveals transient phenotypic adaptation of tubular cells during acute kidney injury. iScience. 2024;27:109255.
     
  4. Curaj A, Vanholder R, Loscalzo J, Quach K, Wu Z, Jankowski V and Jankowski J. Cardiovascular Consequences of Uremic Metabolites: an Overview of the Involved Signaling Pathways. Circ Res. 2024;134:592-613.
     
  5. Mina IK, Mavrogeorgis E, Siwy J, Stojanov R, Mischak H, Latosinska A and Jankowski V. Multiple urinary peptides display distinct sex-specific distribution. Proteomics. 2024;24:e2300227.
     
  6. Shao X, Xu H, Kim H, Ljaz S, Beier F, Jankowski V, Lellig M, Vankann L, Werner JN, Chen L, Ziegler S, Kuppe C, Zenke M, Schneider RK, Hayat S, Saritas T and Kramann R. Generation of a conditional cellular senescence model using proximal tubule cells and fibroblasts from human kidneys. Cell Death Discov. 2024;10:364.
     
  7. Lellig M, Rodriguez M, Lopez-Baltanas R, Hermann J, Wollenhaupt J, Noels H, Zidek W, Tepel M, Mahfoud F, Jankowski J, Munoz-Castaneda JR and Jankowski V. Pyridoxal-5'-phosphate: A cost-effective treatment candidate for hypertensive patients? J Intern Med. 2024;296:435-448.

 

  1. Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, Klug M, Schunk SJ, Schmit D, Kramann R, Korbel C, Ampofo E, Laschke MW, Selejan SR, Paschen A, Herter T, Gaul S, Silbernagel G, Sester M, Sester U, Assmann G, Bals R, Kostner G, Jahnen-Dechent W, Menger MD, Rohrer L, Marz W, Bohm M, Jankowski J, Kopf M, Latz E, Niemeyer BA, Fliser D, Laufs U and Speer T. Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form. Nat Immunol. 2023;24:412-413.
     
  2. Wang J, Liu X, Gu Y, Gao Y, Jankowski V, Was N, Leitz A, Reiss LK, Shi Y, Cai J, Fang Y, Song N, Zhao S, Floege J, Ostendorf T, Ding X and Raffetseder U. DNA binding protein YB-1 is a part of the neutrophil extracellular trap mediation of kidney damage and cross-organ effects. Kidney Int. 2023.
     
  3. Mina IK, Mavrogeorgis E, Siwy J, Stojanov R, Mischak H, Latosinska A and Jankowski V. Multiple urinary peptides display distinct sex-specific distribution. Proteomics. 2023:e2300227.
     
  4. Lohia S, Siwy J, Mavrogeorgis E, Eder S, Thoni S, Mayer G, Mischak H, Vlahou A and Jankowski V. Exploratory Study Analyzing the Urinary Peptidome of T2DM Patients Suggests Changes in ECM but Also Inflammatory and Metabolic Pathways Following GLP-1R Agonist Treatment. Int J Mol Sci. 2023;24.
     
  5.  Lohia S, Latosinska A, Zoidakis J, Makridakis M, Mischak H, Glorieux G, Vlahou A and Jankowski V. Glycosylation Analysis of Urinary Peptidome Highlights IGF2 Glycopeptides in Association with CKD. Int J Mol Sci. 2023;24.
     
  6.  Geisler F, Remmelzwaal S, Jankowski V, Schmidt R, Boxem M and Leube RE. Intermediate filament network perturbation in the C. elegans intestine causes systemic dysfunctions. Elife. 2023;12.

  1. Wu Z, Jankowski V and Jankowski J. Irreversible post-translational modifications - Emerging cardiovascular risk factors. Mol Aspects Med. 2022;86:101010.
     
  2. Thomas K, Zondler L, Ludwig N, Kardell M, Luneburg C, Henke K, Mersmann S, Margraf A, Spieker T, Tekath T, Velic A, Holtmeier R, Hermann J, Jankowski V, Meersch M, Vestweber D, Westphal M, Roth J, Schafers MA, Kellum JA, Lowell CA, Rossaint J and Zarbock A. Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells. JCI Insight. 2022;7.
     
  3. Thomas K, Zondler L, Ludwig N, Kardell M, Luneburg C, Henke K, Mersmann S, Margraf A, Spieker T, Tekath T, Velic A, Holtmeier R, Hermann J, Jankowski V, Meersch M, Vestweber D, Westphal M, Roth J, Schaefers MA, Kellum JA, Lowell CA, Rossaint J and Zarbock A. Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells. JCI Insight. 2022.
     
  4. Rajendiran A, Subramanyam SH, Klemm P, Jankowski V, van Loosdregt J, Vastert B, Vollbach K, Wagner N, Tenbrock K and Ohl K. NRF2/Itaconate Axis Regulates Metabolism and Inflammatory Properties of T Cells in Children with JIA. Antioxidants (Basel). 2022;11.
     
  5. Kaesler N, Schreibing F, Speer T, Puente-Secades S, Rapp N, Drechsler C, Kabgani N, Kuppe C, Boor P, Jankowski V, Schurgers L, Kramann R and Floege J. Altered vitamin K biodistribution and metabolism in experimental and human chronic kidney disease. Kidney Int. 2022;101:338-348.
     
  6. Jiang T, Samapati R, Klassen S, Lei D, Erfinanda L, Jankowski V, Simmons S, Yin J, Arenz C, Dietrich A, Gudermann T, Adam D, Schaefer M, Jankowski J, Flockerzi V, Nusing R, Uhlig S and Kuebler WM. Stimulation of the EP(3) receptor causes lung oedema by activation of TRPC6 in pulmonary endothelial cells. Eur Respir J. 2022;60.
     
  7. Jiang T, Samapati R, Klassen S, Lei D, Erfinanda L, Jankowski V, Simmons S, Yin J, Arenz C, Dietrich A, Gudermann T, Adam D, Schaefer M, Jankowski J, Flockerzi V, Nusing R, Uhlig S and Kuebler WM. Stimulation of the EP3 receptor causes lung edema by activation of TRPC6 in pulmonary endothelial cells. Eur Respir J. 2022.
     
  8. Jankowski V, Saritas T, Kjolby M, Hermann J, Speer T, Himmelsbach A, Mahr K, Heuschkel MA, Schunk SJ, Thirup S, Winther S, Bottcher M, Nyegard M, Nykjaer A, Kramann R, Kaesler N, Jankowski J, Floege J, Marx N and Goettsch C. Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease. Kidney Int. 2022;101:574-584.
     
  9. Hermann J, Schurgers L and Jankowski V. Identification and characterization of post-translational modifications: Clinical implications. Mol Aspects Med. 2022;86:101066.


Stand: Feb 2023

  1. Wu Z, Jankowski V and Jankowski J. Irreversible post-translational modifications - Emerging cardiovascular risk factors. Mol Aspects Med. 2021:101010.
     
  2. Vlahou A, Hallinan D, Apweiler R, Argiles A, Beige J, Benigni A, Bischoff R, Black PC, Boehm F, Ceraline J, Chrousos GP, Delles C, Evenepoel P, Fridolin I, Glorieux G, van Gool AJ, Heidegger I, Ioannidis JPA, Jankowski J, Jankowski V, Jeronimo C, Kamat AM, Masereeuw R, Mayer G, Mischak H, Ortiz A, Remuzzi G, Rossing P, Schanstra JP, Schmitz-Drager BJ, Spasovski G, Staessen JA, Stamatialis D, Stenvinkel P, Wanner C, Williams SB, Zannad F, Zoccali C and Vanholder R. Data Sharing Under the General Data Protection Regulation: Time to Harmonize Law and Research Ethics? Hypertension. 2021;77:1029-1035.
     
  3. Schunk SJ, Hermann J, Sarakpi T, Triem S, Lellig M, Hahm E, Zewinger S, Schmit D, Becker E, Mollmann J, Lehrke M, Kramann R, Boor P, Lipp P, Laufs U, Marz W, Reiser J, Jankowski J, Fliser D, Speer T and Jankowski V. Guanidinylated Apolipoprotein C3 (ApoC3) Associates with Kidney and Vascular Injury. J Am Soc Nephrol. 2021.
     
  4. Saar-Kovrov V, Zidek W, Orth-Alampour S, Fliser D, Jankowski V, Biessen EAL and Jankowski J. Reduction of protein-bound uraemic toxins in plasma of chronic renal failure patients: A systematic review.J Intern Med. 2021;290:499-526.
     
  5. Orth-Alampour S, Gayrard N, Salem S, Bhargava S, Jankowski V, Jover B, Notarnicola C, Noels H, van der Vorst EPC, Kuppe C, Wolf M, Goettsch C, Theelen W, Bruck H, Fliser D, Loscalzo J, Wu Z, Marx N, Zidek W, Argiles A and Jankowski J. Prevention of vascular calcification by the endogenous chromogranin A-derived mediator that inhibits osteogenic transdifferentiation. Basic Res Cardiol. 2021;116:57.
     
  6. Mavrogeorgis E, Mischak H, Latosinska A, Siwy J, Jankowski V and Jankowski J. Reproducibility Evaluation of Urinary Peptide Detection Using CE-MS. Molecules. 2021;26.
     
  7. King RJ, Schuett K, Tiede C, Jankowski V, John V, Trehan A, Simmons K, Ponnambalam S, Storey RF, Fishwick CWG, McPherson MJ, Tomlinson DC and Ajjan RA. Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk.Haematologica. 2021;106:1616-1623.
     
  8. Kaesler N, Schreibing F, Speer T, Puente-Secades S, Rapp N, Drechsler C, Kabgani N, Kuppe C, Boor P, Jankowski V, Schurgers L, Kramann R and Floege J. Altered vitamin K biodistribution and metabolism in experimental and human chronic kidney disease. Kidney Int. 2021.
     
  9. Jankowski V, Saritas T, Kjolby M, Hermann J, Speer T, Himmelsbach A, Mahr K, Heuschkel MA, Schunk SJ, Thirup S, Winther S, Bottcher M, Nyegard M, Nykjaer A, Kramann R, Kaesler N, Jankowski J, Floege J, Marx N and Goettsch C. Carbamylated sortilin associates with cardiovascular calcification in patients with chronic kidney disease. Kidney Int. 2021.
     
  10. Hermann J, Brehmer K, Jankowski V, Lellig M, Hohl M, Mahfoud F, Speer T, Schunk SJ, Tschernig T, Thiele H and Jankowski J. Registration of Image Modalities for Analyses of Tissue Samples Using 3D Image Modelling. Proteomics Clin Appl. 2021;15:e2170024.
     
  11. He T, Pejchinovski M, Mullen W, Beige J, Mischak H and Jankowski V. Peptides in Plasma, Urine, and Dialysate: Toward Unravelling Renal Peptide Handling. Proteomics Clin Appl. 2021;15:e2000029.
     
  12. He T, Mischak M, Clark AL, Campbell RT, Delles C, Diez J, Filippatos G, Mebazaa A, McMurray JJV, Gonzalez A, Raad J, Stroggilos R, Bosselmann HS, Campbell A, Kerr SM, Jackson CE, Cannon JA, Schou M, Girerd N, Rossignol P, McConnachie A, Rossing K, Schanstra JP, Zannad F, Vlahou A, Mullen W, Jankowski V, Mischak H, Zhang Z, Staessen JA and Latosinska A. Urinary peptides in heart failure: a link to molecular pathophysiology. Eur J Heart Fail. 2021.
     
  13. He T, Melgarejo JD, Clark AL, Yu YL, Thijs L, Diez J, Lopez B, Gonzalez A, Cleland JG, Schanstra JP, Vlahou A, Latosinska A, Mischak H, Staessen JA, Zhang ZY and Jankowski V. Serum and urinary biomarkers of collagen type-I turnover predict prognosis in patients with heart failure. Clin Transl Med. 2021;11:e267.
  1. Zewinger S, Reiser J, Jankowski V, Alansary D, Hahm E, Triem S, Klug M, Schunk SJ, Schmit D, Kramann R, Korbel C, Ampofo E, Laschke MW, Selejan SR, Paschen A, Herter T, Schuster S, Silbernagel G, Sester M, Sester U, Assmann G, Bals R, Kostner G, Jahnen-Dechent W, Menger MD, Rohrer L, Marz W, Bohm M, Jankowski J, Kopf M, Latz E, Niemeyer BA, Fliser D, Laufs U and Speer T. Apolipoprotein C3 induces inflammation and organ damage by alternative inflammasome activation. Nat Immunol. 2020;21:30-41.
     
  2. Nazir S, Jankowski V, Bender G, Zewinger S, Rye KA and van der Vorst EPC. Interaction between high-density lipoproteins and inflammation: Function matters more than concentration! Adv Drug Deliv Rev. 2020;159:94-119.
     
  3. Hermann J, Noels H, Theelen W, Lellig M, Orth-Alampour S, Boor P, Jankowski V and Jankowski J. Sample preparation of formalin-fixed paraffin-embedded tissue sections for MALDI-mass spectrometry imaging. Anal Bioanal Chem. 2020;412:1263-1275.
     
  4. He T, Siwy J, Metzger J, Mullen W, Mischak H, Schanstra JP, Zurbig P and Jankowski V. Associations of urinary polymeric immunoglobulin receptor peptides in the context of cardio-renal syndrome.Sci Rep. 2020;10:8291.
     
  5. Curaj A, Schumacher D, Rusu M, Staudt M, Li X, Simsekyilmaz S, Jankowski V, Jankowski J, Dumitrascu AR, Hausenloy DJ, Schuh A and Liehn EA. Neutrophils Modulate Fibroblast Function and Promote Healing and Scar Formation after Murine Myocardial Infarction. Int J Mol Sci. 2020;21.
     
  6. Breitkopf DM, Jankowski V, Ohl K, Hermann J, Hermert D, Tenbrock K, Liu X, Martin IV, Wang J, Groll F, Grone E, Floege J, Ostendorf T, Rauen T and Raffetseder U. The YB-1:Notch-3 axis modulates immune cell responses and organ damage in systemic lupus erythematosus. Kidney Int. 2020;97:289-303.
  1. Zhou, Z., Matsumoto, T., Jankowski, V., Pernow, J., Mustafa, S. J., Duncker, D. J. & Merkus, D. Uridine adenosine tetraphosphate and purinergic signaling in cardiovascular system: An update. Pharmacol Res 141, 32-45, doi:10.1016/j.phrs.2018.12.009 (2019).
     
  2. Vollmer, T., Ljungberg, B., Jankowski, V., Jankowski, J., Glorieux, G. & Stegmayr, B. G. An in-vitro assay using human spermatozoa to detect toxicity of biologically active substances. Sci Rep 9, 14525, doi:10.1038/s41598-019-50929-z (2019).
     
  3. van der Made, T. K., Fedecostante, M., Scotcher, D., Rostami-Hodjegan, A., Sastre Torano, J., Middel, I., Koster, A. S., Gerritsen, K. G., Jankowski, V., Jankowski, J., Hoenderop, J. G. J., Masereeuw, R. & Galetin, A. Quantitative Translation of Microfluidic Transporter in Vitro Data to in Vivo Reveals Impaired Albumin-Facilitated Indoxyl Sulfate Secretion in Chronic Kidney Disease. Mol Pharm 16, 4551-4562, doi:10.1021/acs.molpharmaceut.9b00681 (2019).
     
  4. Sternkopf, M., Thoroe-Boveleth, S., Beck, T., Oleschko, K., Erlenkotter, A., Tschulena, U., Steppan, S., Speer, T., Goettsch, C., Jankowski, V., Jankowski, J., Noels, H. & European Uremic Toxin Work Group, E. A Bifunctional Adsorber Particle for the Removal of Hydrophobic Uremic Toxins from Whole Blood of Renal Failure Patients. Toxins (Basel) 11, doi:10.3390/toxins11070389 (2019).
     
  5. Schumacher, D., Alampour-Rajabi, S., Ponomariov, V., Curaj, A., Wu, Z., Staudt, M., Rusu, M., Jankowski, V., Marx, N., Jankowski, J., Brandenburg, V., Liehn, E. A. & Schuh, A. Cardiac FGF23: new insights into the role and function of FGF23 after acute myocardial infarction. Cardiovasc Pathol 40, 47-54, doi:10.1016/j.carpath.2019.02.001 (2019).
     
  6. Gajjala, P. R., Bruck, H., Noels, H., Heinze, G., Ceccarelli, F., Kribben, A., Saez-Rodriguez, J., Marx, N., Zidek, W., Jankowski, J. & Jankowski, V. Novel plasma peptide markers involved in the pathology of CKD identified using mass spectrometric approach. J Mol Med (Berl) 97, 1451-1463, doi:10.1007/s00109-019-01823-8 (2019).
     
  7. Belczacka, I., Pejchinovski, M., Krochmal, M., Magalhaes, P., Frantzi, M., Mullen, W., Vlahou, A., Mischak, H. & Jankowski, V. Urinary Glycopeptide Analysis for the Investigation of Novel Biomarkers. Proteomics Clin Appl 13, e1800111, doi:10.1002/prca.201800111 (2019).
     
  8. Belczacka, I., Latosinska, A., Siwy, J., Metzger, J., Merseburger, A. S., Mischak, H., Vlahou, A., Frantzi, M. & Jankowski, V. Author Correction: Urinary CE-MS peptide marker pattern for detection of solid tumors. Sci Rep 9, 12864, doi:10.1038/s41598-019-49304-9 (2019).
  1. Sawant, M., Schwarz, N., Windoffer, R., Magin, T. M., Krieger, J., Mucke, N., Obara, B., Jankowski, V., Jankowski, J., Wally, V., Lettner, T. & Leube, R. E. Threonine 150 Phosphorylation of Keratin 5 Is Linked to Epidermolysis Bullosa Simplex and Regulates Filament Assembly and Cell Viability. J Invest Dermatol 138, 627-636, doi:10.1016/j.jid.2017.10.011 (2018).
     
  2. Noels, H., Theelen, W., Sternkopf, M., Jankowski, V., Moellmann, J., Kraemer, S., Lehrke, M., Marx, N., Martin, L., Marx, G., Jankowski, J., Goetzenich, A. & Stoppe, C. Reduced post-operative DPP4 activity associated with worse patient outcome after cardiac surgery. Sci Rep 8, 11820, doi:10.1038/s41598-018-30235-w (2018).
     
  3. Noels, H., Boor, P., Goettsch, C., Hohl, M., Jahnen-Dechent, W., Jankowski, V., Kindermann, I., Kramann, R., Lehrke, M., Linz, D., Maack, C., Niemeyer, B., Roma, L. P., Schuett, K., Speer, T., Wagenpfeil, S., Werner, C., Zewinger, S., Bohm, M., Marx, N., Floege, J., Fliser, D. & Jankowski, J. The new SFB/TRR219 Research Centre. Eur Heart J 39, 975-977, doi:10.1093/eurheartj/ehy083 (2018).
     
  4. Moellmann, J., Klinkhammer, B. M., Onstein, J., Stohr, R., Jankowski, V., Jankowski, J., Lebherz, C., Tacke, F., Marx, N., Boor, P. & Lehrke, M. Glucagon-Like Peptide 1 and Its Cleavage Products Are Renoprotective in Murine Diabetic Nephropathy. Diabetes 67, 2410-2419, doi:10.2337/db17-1212 (2018).
     
  5. Kork, F., Jankowski, J., Goswami, A., Weis, J., Brook, G., Yamoah, A., Anink, J., Aronica, E., Fritz, S., Huck, C., Schipke, C., Peters, O., Tepel, M., Noels, H. & Jankowski, V. Golgin A4 in CSF and granulovacuolar degenerations of patients with Alzheimer disease. Neurology 91, e1799-e1808, doi:10.1212/WNL.0000000000006457 (2018).
     
  6. Belczacka, I., Latosinska, A., Siwy, J., Metzger, J., Merseburger, A. S., Mischak, H., Vlahou, A., Frantzi, M. & Jankowski, V. Urinary CE-MS peptide marker pattern for detection of solid tumors. Sci Rep 8, 5227, doi:10.1038/s41598-018-23585-y (2018).
  1. Schuett, K., Savvaidis, A., Maxeiner, S., Lysaja, K., Jankowski, V., Schirmer, S. H., Dimkovic, N., Boor, P., Kaesler, N., Dekker, F. W., Floege, J., Marx, N. & Schlieper, G. Clot Structure: A Potent Mortality Risk Factor in Patients on Hemodialysis. J Am Soc Nephrol 28, 1622-1630, doi:10.1681/ASN.2016030336 (2017).
     
  2. Pejchinovski, M., Siwy, J., Metzger, J., Dakna, M., Mischak, H., Klein, J., Jankowski, V., Bae, K. T., Chapman, A. B. & Kistler, A. D. Urine peptidome analysis predicts risk of end-stage renal disease and reveals proteolytic pathways involved in autosomal dominant polycystic kidney disease progression. Nephrol Dial Transplant 32, 487-497, doi:10.1093/ndt/gfw243 (2017).
     
  3. Gajjala, P. R., Jankowski, V., Heinze, G., Bilo, G., Zanchetti, A., Noels, H., Liehn, E., Perco, P., Schulz, A., Delles, C., Kork, F., Biessen, E., Narkiewicz, K., Kawecka-Jaszcz, K., Floege, J., Soranna, D., Zidek, W. & Jankowski, J. Proteomic-Biostatistic Integrated Approach for Finding the Underlying Molecular Determinants of Hypertension in Human Plasma. Hypertension 70, 412-419, doi:10.1161/HYPERTENSIONAHA.116.08906 (2017).