The Department of Haematology, Oncology, Haemostaseology and Stem Cell Transplantation (Department of Medicine IV) - AG Koschmieder (MED IV)- is offering a position to work on the project entitled "Targeting the hematopoietic VEGF-VEGFR axis in Myeloproliferative Neoplasm progression" for a
PhD student (f/m/d) Biology, biochemistry, biomedicine, biotechnology or related biosciences
The position is currently available at 65% (25,025 hours/week) part-time and initially limited until 31.10.2027 with an option of prolongation up to the completion of the doctoral degree.
Roles and responsibilities
The successful applicant will conduct the scientific investigation of the VEGF-VEGFR signaling pathway in hematological malignancies. The project is integrated in ongoing studies of our group, focused on myeloid leukemias. The applicant will also be in direct collaboration with other investigators in our lab and collaborator research groups in Germany and abroad.
- Perform cell culture (mono and coculture) with primary cells, cell lines and induced pluripotent stem cells (iPSC) and iPSC-derived organoids and in vivo work with transgenic and xenograft murine models
- Cellular and molecular characterization (flow cytometry, immunofluorescence, RT-PCR, RNA-seq, scRNAseq) of disease-associated pathways
- Histological analysis of murine and patient samples
- Drug screening in vitro and in vivo validation
Your background
- Master/Diploma degree (preferentially biology, biochemistry, biotechnology, cell biology)
- Experience in tissue culture work, molecular biology and biochemistry
- Highly motivated, with the desire to work independently in an international team
- Desirable:
- In vivo work experience
- iPS cell culture experience
- Excellent organization and planning
- Critical thinking and independent work
- High motivation and Teamwork spirit
- Good communication in written and spoken english (Level C1)
Why should you choose us?
- Salary in accordance with provisions based on german TV-L (EG 13)
- 30 days vacation/year for full-time employees
- Employees who recruit employees for nursing care get a bonus of 3,000 euros
- An attractive VBL company pension scheme
- Further education and training opportunities
- Attractive conditions for local traffic transport system
- A company kindergarten (places subject to availability)
- Staff residence (places subject to availability and by arrangement)
- An onboarding app for new employees
- Extended opening hours for our staff restaurant
This position is not gender specific.
The RWTH Aachen University Hospital promotes equal opportunities and diversity. Applications from women are expressly encouraged and if the applicant is suitable qualified, they will be given priority in accordance with the LGG. If suitably qualified, people with a registered disability will also receive priority.
Weekly hours are negotiable.
You should preferably use our digital application portal at www.karriere.ukaachen.de for your application. There you have the option of securing your documents in the electronic application folder to prevent unauthorized access. Applications that reach us by email to: bewerbung@ukaachen.de (this transmission path cannot be as effectively secured) will be transferred to the aforementioned portal and any accompanying documents will be disposed of in accordance with data protection regulations immediately after transfer. After the retention period has expired, the data in the portal will also be deleted. If you do not agree to a transfer to the Application portal your application cannot be considered
The application deadline for the advertised positione GB-P-49411 endet am 22.11.2024.
Uniklinik RWTH Aachen, Department of Haematology, Oncology, Haemostaseology and Stem Cell Transplantation (Department of Medicine IV), Pauwelsstraße 30, 52074 Aachen.
For more detailed information please contact Dr. rer. nat. Marcelo Augusto Szymanski de Toledo, Tel.: +49 (0)241-80 80986, E-Mail: mszymanskideukaachende
