The Clinic of General, Visceral, Pediatric, and Transplant Surgery -Research Group “Molecular Tumor Biology”, (Leader Univ.-Prof. Dr. T. Cramer) is offering a position for a
PhD Student (f/m/d) on “Tumor Biology of human Hepatocellular Carcinoma“
The part-time position 65% (25,025 hours/week) will start as soon as possible and is initially limited for 3 years with the possibility of prolongation.
In this project, funded by the German Federal Ministry for Education and Research, we will identify key mechanisms of the transition from liver fibrosis/cirrhosis to Hepatocellular Carcinoma (HCC). The project is being carried out within the framework of a Germany-wide research consortium called “LiSym Cancer” (www.lisym-cancer.org). The overarching aim of the consortium is to develop a systems medicine-based algorithm to identify patients at high risk for HCC.
Your tasks
- Isolation of human liver cells and culture as 3D organoids
- Treatment of 3D organoids with different agents to analyze the effect on tumor cell survival
- Modulation of cells with CRISPR technology
- Functional testing of the interaction of tumor cells with immune cells and fibroblasts
- Scientific publication of the results
Your profile
- Master’s degree in either biology, biochemistry or comparable degrees in natural sciences
- A strong interest in hepatology, oncology and cell biology
- Very good English skills (in writing and speaking) LevelC1
- Enthusiasm to work in an international team with widespread collaborators
Why should you choose us?
- A performance-related salary in accordance with the provisions of the TV-L (EG 13)
- We provide a highly interactive and well-equipped environment, in an international team, with excellent partners, a broad spectrum of methods and a highly relevant research topic
- Contribution to a translational and clinically relevant project
- 30 days vacation/year for full-time employees
- Employees recruit employees for nursing care / bonus of 3,000 euros
- An attractive VBL company pension scheme
- Further education and training opportunities
- Attractive conditions for public transport
- A company kindergarten (places subject to availability)
- Staff residence (places subject to availability and by arrangement)
- An onboarding app for new employees
- Extended opening hours for our staff restaurant
This position is not gender specific.
The RWTH Aachen University Hospital promotes equal opportunities and diversity. Applications from women are expressly encouraged and if the applicant is suitable qualified, they will be given priority in accordance with the LGG. If suitably qualified, people with a registered disability will also receive priority.
Weekly hours are negotiable.
You should preferably use our digital application portal at www.karriere.ukaachen.de for your application. There you have the option of securing your documents in the electronic application folder to prevent unauthorized access. Applications that reach us by email to: bewerbung@ukaachen.de (this transmission path cannot be as effectively secured) will be transferred to the aforementioned portal and any accompanying documents will be disposed of in accordance with data protection regulations immediately after transfer. After the retention period has expired, the data in the portal will also be deleted. If you do not agree to a transfer to the Application portal your application cannot be considered.
Please include (1) a cover letter, which specifically emphasizes your interest in this project, (2) CV with publication list, (3) contacts of two references, and (4) copies of the most important certificates (with grades).
The application deadline for the advertised positione GB-P-49279 is 15.11.2024.
Uniklinik RWTH Aachen, Clinic of General, Visceral, Pediatric, and Transplant Surgery -Research Group “Molecular Tumor Biology”, Leader Univ.-Prof. Dr. med. Thorsten Cramer, Pauwelsstraße 30, 52074 Aachen.
For more detailed information please contact Thorsten Cramer, E-Mail: tcramerukaachende
