Inside the network.

aixCAVE, a five-sided immersive virtual reality environment at the IT Center RWTH Aachen,  allows a glimpse of the amazing intricacies of the keratin cytoskeleton. Walking through the digitalized network at nm resolution provides stunning vistas and novel insights into network architecture. The experience spurs quantitative assessment using innovative image analysis tools. The expected insights will help to understand the role of the keratin cytoskeleton for the homeostasis and maintenance of surface-lining epithelia and will have implications for the understanding and treatment of diseases ranging from genetically transmitted skin diseases to carcinogenesis.