Welcome to the Website of the Institute of Physiology!
The Institute of Physiology is one of three Physiological Institutes. Our research has a focus on ion channels. Ion channels are the basis of neuronal excitability and of communication between neurons. Mutations in ion channels can lead to diseases and malregulation of ion channels determines the clinical picture of many diseases. The analysis of ion channels in molecular detail contributes to a better understanding of their pathophysiological role and is the basis for an educated pharmacotherapy. In addition, the group of Khosrow Mottaghy works on artificial organs, in particular on extracorporeal circulation.
On our website you can find the most relevant information on us and on our research. We strive for a high quality in teaching. More information on our teaching and on the history of the Institute can be found here (in German only).
Yours sincerely
Stefan Gründer
News from the Institute of Physiology
News
01.06.2026 – Dr. Jennifer Noonan moves from the Humboldt-University Berlin to work at the Institute of Physiology
On June 1st, Dr. Jennifer Noonan started her work as a scientist at the Institute of Physiology. Dr. Noonan studied at the renowned McGill University in Montreal, Canada, where she also did her PhD on…
01.06.2026 – Thyroid hormones are positive allosteric modulators of Acid-sensing ion channels
In our last study, which has been published in Neuropharmacology, we discovered that the thyroid hormones triiodothyronine (T3) und thyroxine (T4) are positive allosteric modulators of Acid-sensing…
The evolution of inhibitory signaling
Finally published in Advanced Science, the premium open access journal of Wiley: our phylogenetic and functional characterization of pentameric ligand-gated ion channels (pLGICs) from the cnidarian…
Nina Boersch successfully finished her MD thesis.
Today our MD student Nina Boersch successfully passed the oral examination at the end of her doctoral thesis, which is entitled „ASICs-dependent acid-induced cell death”. She now works as a physician…
![[Translate to Englisch:]](/fileadmin/files/institute/physiologie/_processed_/0/9/csm_Felicitas_Weiss_Promoion_82e8faae40.png "[Translate to Englisch:]")
Felicitas Weiß successfully finished her MD thesis
Today our MD student Felicitas Weiß successfully passed the oral examination at the end of her doctoral thesis, which is entitled „Biochemical analysis of the interaction of ASIC1a and Prenylcysteine…
04.03.2026 – Nikolai Ratajczak successfully finished his MD thesis
Today our MD student Nikolai Ratajczak successfully passed the oral examination at the end of his doctoral thesis, which is entitled „Modulatory influence of PCOL on ASIC1a: electrophysiological…
Stefan Gründer joins Pflügers Archiv – European Journal of Physiology as Associate Editor
On January 1st, 2026, Stefan Gründer joined Pflügers Archiv – European Journal of Physiology as an Associate Editor. Pflügers Archiv is the official journal of the German Physiological Society and…
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Jingyu Yang successfully finished her PhD thesis
Today our PhD student Jingyu Yang successfully defended her dissertation entitled "BASIC Deficiency Disrupts Hepatic Metabolism and Pancreatic α-Cell Function during Fasting". We sincerelycongratulate…
15.01.2026 – Lu Qin successfully finished his PhD thesis
Today our PhD student Lu Qin successfully defended his dissertation entitled "Electrophysiological Characterization of Subtype-Specific Modulation and Activation of Acid-Sensing Ion Channel and…
Paper of the month: Preisträger Dr. Sven Kuspiel, Prof. Dr. Stefan Gründer & Dr. Dominik Wiemuth
In der Forschungsarbeit von Dr. Sven Kuspiel, Prof. Dr. Stefan Gründer, Dr. Dominik Wiemuth und ihrem Team wird untersucht, ob ein im Nervensystem vorkommender Ionenkanal Komplexe mit anderen…
Anton Richter successfully finished his MD thesis
Today our MD student Anton Richter successfully passed the oral examination at the end of his doctoral thesis, which is entitled „Investigations on the ASIC-dependent acid-induced cell death”. Anton…
Post-Doc (w/m/d) im Bereich Neuronaler Ionenkanäle gesucht
Das Institut für Physiologie an der Uniklinik RWTH Aachen besetzt eine Stelle als
Post-Doc (w/m/d) im Bereich Neuronaler Ionenkanäle
mit 100 Prozent der vollen tariflich vereinbarten Arbeitszeit…
