Functional characterization of Acid-Sensing Ion Channels in Glioblastoma stem cell lines

Typically, the tumor microenvironment has a slightly acidic pH. In our most recent study, which was published in the journal Pflügers Archiv – European Journal of Physiology, we functionally…

What ist he role of acid-sensing ion channels in tumour cells??

Acid-sensing ion channels (ASICs) are proton-gated Na+-channels, which are normally expressed in neurons. However, also many tumour cells express ASICs. Because tumour cells thrive in an acidic…

High concentrations of the pineal hormone melatonin have profound effects on neuronal excitability

Melatonin is well known as “sleeping hormone”. In the USA and Canada, it is also sold as an over-the-counter dietary supplement and strong antioxidative effects and positive effects on diverse…

Calendar of events
To the calendar of events of the Uniklinik RWTH Aachen